Aga Khan University’s Brain & Mind Institute Launches The Brain Resilience Study In Kenya

In a bid to redefine the future of aging in Africa, the Aga Khan University‘s Brain and Mind Institute (AKU-BMI) today launched the Brain Resilience Kenya Project.

This pioneering initiative, supported by Wellcome Leap and Temasek Trust, aims to explore the hidden factors that keep the brain sharp and resilient even in the face of life’s toughest challenges like illness, poverty, and climate change.

The study’s findings could hold the key to healthier, more resilient aging for millions across the continent.

Led by principal investigators Drs. Chi Udeh-Momoh and Karen Blackmon from the Brain and Mind Institute, along with Clinical Research Unit (CRU) Director Professor Mansoor Saleh, the study will focus on both healthy adults and those recently diagnosed with cancer, providing a unique opportunity to compare the effects of stressors like illness on brain resilience.

By combining culturally tailored assessments with advanced statistical and machine learning techniques, the study is set to uncover the key factors that enhance brain resilience.

The Brain Resilience Kenya Project is collaborating with world-leading institutions, including University College London, University of California San Francisco, Karolinska Institute, Dartmouth and Wake Forest University, and Imperial College London, highlighting the global importance of this research.

While speaking on behalf of the MOH Director General Dr. Patrick Amoth, the Acting MOH Director of Curative and Nursing Services Dr. Rebecca Kiptui stressed the significance of this study in enhancing brain health and resilience in Kenya.

“This initiative is a pivotal advancement in our national efforts to address the critical issue of brain ageing and resilience, particularly as it affects our aging population. The Brain Resilience Kenya Project is not merely a research endeavour but a strategic intervention that aligns with our broader public health goals. This project will enable us to better understand the determinants of brain ageing and to develop targeted interventions that can be implemented at the community level.”   

Dr. Zul Merali, Founding Director of the Brain and Mind Institute, highlighted that the study underscores the institute’s dedication to advancing research on critical brain health challenges faced by African populations. “This initiative represents a significant step forward in understanding how various stressors affect brain aging in East African communities. The insights we gain will not only deepen our understanding of stress and resilience but also pave the way for impactful interventions that enhance mental health and well-being across the continent.”

Dr. Chi Udeh-Momoh, Translational Neuroscientist at the Aga Khan University’s Brain & Mind Institute emphasized the transformative potential of the study “We are uncovering the secrets of lifelong brain health by closely examining the unique experiences and resilience factors within Kenyan communities. Our goal is to build a comprehensive framework that supports brain health from adulthood through old age, ultimately contributing to a society where individuals can thrive mentally and cognitively despite facing various life challenges. This study has the potential to inform policies and practices that enhance quality of life and reduce the burden of age-related brain ageing and resilience.”

Professor Mansoor Saleh, Director of the Clinical Research Unit (CRU) at the Aga Khan University, added, “Understanding the biological and psychological factors that contribute to brain resilience, especially in individuals recently diagnosed with cancer, is critical to developing interventions that can help individuals maintain cognitive health even in the face of significant stressors. By focusing on diverse populations and leveraging cutting-edge research methodologies, the Brain Resilience Kenya Project is poised to make a meaningful impact on how we approach brain health in Africa and beyond.”

The Brain Resilience Kenya Project will collaborate closely with local communities, gathering valuable insights into coping mechanisms and resilience-building strategies that can be translated into effective, culturally relevant interventions.

As the study progresses, it promises to yield critical findings that will shape future research and interventions aimed at promoting healthy brain aging not only in Kenya but across the African continent and beyond.